HIV prevention

We will consider HIV prevention work in HIV endemic Sub-Saharan Africa. Cost effectiveness varies by a factor of 60 between different interventions (Cost-Effectiveness of HIV Prevention in Developing Countries). The interventions we consider are:

  • Sex worker STD and condom programs for female sex workers: $8-12/case averted
  • General population STD control: $350/case averted
  • General population voluntary counseling and testing: $249-$346/case averted
  • General population safe blood supply: $172/case averted
  • General population prevention of mother to child transmission: $298-$506/case averted

Leverage Factor (sex workers in the absence of treatment)

This giving opportunity is a sensitive one. It would be difficult for the US Agency for International Development to proclaim that their number one priority was the provision of condoms to foreign prostitutes, but that is precisely what they should do. In fact, in a backwards step, the US governement requires organizations receiving HIV/AIDS funding to explicitly oppose prostitution. On the other hand The Bill and Melinda Gates Foundation has proven wiser and is replicating the Kolkata Durbar sex worker HIV project to other states in India.

Imagine a terrorist about to detonate a bomb that will kill 100 people that happen to be nearby. How many billions of dollars should the government spend to stop that terrorist? Now imagine a prostitute infected with HIV that will kill 100 clients, as well as the "innocent" spouses of those clients. How much should the government spend to stop them? The answer would seem to be as close to zero as is imaginable. I have searched, and checked with Funders Concerned About AIDS but amongst U.S. NGOs, I am not aware of a single 501(c)3 charitable organization that focuses solely on HIV prevention amongst sex workers, despite this having a huge charitable payoff.

Reported effectiveness of programs for sex workers is:

The difference between the effectiveness of the different programs is probably primarily a result of the difference in these countries HIV infection rates. An intervention program will be far more effective when the HIV prevalance rate is high. In Kenya the sex worker HIV prevelance rate is 81% in 1986 to below 50% after 1997 for Nairobi, which we linearly approximate as 67% (circa 1991; the time of the reported Nairobi cost-effectiveness paper), in Ahmedabad the sex worker HIV prevelance rate is 12% (1999). In India overall according to UNAIDS the sex worker HIV prevelance is 4.9% (as retrieved 2011).

Project

HIV prevention

Cost

$50-500/case averted

Real world outcome

prevent 1 HIV infection

Outcome estimates

Scaling the Ahmedabad infection rate to that of Kenya gives a $10-39/case averted range. Very roughly scaling the Avahan project using the all of India sex worker infection rate gives $90-$730/case averted. Combining the Kenya, Ahmedabad, and Avahan data, and weighting towards Avahan because it seems more credible, it seems reasonable to assume the actual cost per case averted in an HIV endemic country is probably somewhere in the $50-500/case averted range.

Economic value in Western terms

$2m/case averted

Leverage Factor

4,000 - 40,000 in a HIV endemic population


Leverage Factor (general population in the absence of treatment)

We also consider a different prevention package to see if it produces similar results. Which it does not. It gives lower results, widening our confidence interval.

The difference between the effectiveness of these two programs is probably primarily a result of the difference in these countries HIV infection rates. An intervention program will be far more effective when the HIV prevalance rate is high. In Kenya the sex worker HIV prevelance rate is 27%, in Gujarat the sex worker HIV prevelance rate is 6.5%.

Project

HIV prevention

Cost

$172-506/case averted (above)

$1,250/case averted (Solutions to the World's Biggest Problems, Bjorn Lomborg, 2007, pp. 326; $2.5b/yr to prevent 2m infections/yr)

Real world outcome

prevent 1 HIV infection

Economic value in Western terms

$2m/case averted

Leverage Factor

1,500 - 12,000


Leverage Factor (sex workers in the presence of treatment)
Project

HIV prevention

Cost

$10-40/case averted (see sex workers in the absence of treatment)

Real world outcome

prevent 1 HIV infection

Outcome estimates

infection would cost $300/case/year for ART; capitalize costs over standard time period

Economic value in Western terms

$6k/case averted

Leverage Factor

150 - 600


Leverage Factor (general population in the presence of treatment)
Project

HIV prevention

Cost

$172-506/case averted (above)

$1,250/case averted (Solutions to the World's Biggest Problems, Bjorn Lomborg, 2007, pp. 326; $2.5b/yr to prevent 2m infections/yr)

Real world outcome

prevent 1 HIV infection

Outcome estimates

infection would cost $300/case/year for ART; capitalize costs over standard time period

Economic value in Western terms

$6k/case averted

Leverage Factor

5 - 30